The spine is a frequent site affected by tumors and cancers both arising in the spine and those spreading from other sites in the body. The tumors that commonly affect the spine are Osteoid osteoma, Osteoblastoma, Aneurysmal Bone Cyst, Giant cell tumor, Eosinophilic granuloma, lymphoma and Plasmacytoma. The cancers that commonly affect the spine primarily are Multiple Myeloma, Leukemia, Ewing’s Sarcoma, Osteosarcoma and Chondrosarcoma.
The cancers that spread to the spine (metastasis) from other sites in the body are prostrate cancer, breast cancer, lung cancer, thyroid cancer and renal cancer. Of these, prostrate cancer and breast cancer metastasis are bone forming (osteoblastic or osteosclerotic) whereas the other cancers are bone destroying (osteolytic).